My pred forte expired in 1998 would it be safe to use June 20,2010? Updated 21 Jun 2010 • 2 answers Claritin 24 Hour Allergy - Is it safe to take Claritin with enlarged prostate? Loratadine is an anti-histamine. It's major side-effect (not common) is drowsiness. It is safe to take it after the expiration date. Depending on how long after, it may simply have a weaker effect. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Mumneh on taking expired claritin: Nyquil contains a sedating antihistamine and Claritin (loratadine) is a non-sedating antihistamine. It is very unlikely that there would be adverse effects from taking these at the same time at usual doses. How to use Loratadine. If you are using the over-the-counter product to self-treat, read all the directions on the product package before taking this medication. Originally Answered: Is it safe to take expired Claritin? Loratadine (claritin) and all medications have expiration dates that are based on stability and efficacy studies by the manufacturer. It is the last date they can state that the medication, if stored in the recommended manner which in the case would be room temp, is viable. As a general rule of thumb, it is not recommended to take expired Claritin (loratadine), or any medication that is past the manufacturer set expiration date for that matter. Related Questions Is it safe to take an expired children's claritin (loratadine)? Is it safe to take 20 mg loratadine? Is it ok to take Claritin (loratadine) D that expired March of 2014? Is it safe to take, or should you brave the haze of pollen to get a fresh supply at the drugstore? In general, expired drugs aren’t likely to kill you, but there are some things you should know. I would take them if I were you. My doctor friends tell me that it's ok to take most expired otc meds (vitamins, asprin etc.) They wont do you any harm, they're just not full strength anymore. Loratadine comes in capsules, tablets, and as syrup. Loratadine should not be given to children under that age 6. You should not take more than 10 milligram (mg), which is one tablet or capsule.